Polynucleotide
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Polynucleotide treatments are the latest generation of injectable skin boosters, offering powerful skin regeneration by using DNA fragments derived from salmon or trout sperm (yes, really!) to stimulate cellular repair, collagen production, and tissue regeneration.
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What Are Polynucleotides?
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Polynucleotides (PNs) are long chains of nucleotides, the building blocks of DNA and RNA.
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In aesthetic medicine, these purified, biocompatible molecules support skin healing, improve elasticity, and enhance hydration—especially for tired, thin, or damaged skin.
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How Do They Work
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Stimulate fibroblast activity → increases collagen and elastin production
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Hydrate skin deeply → attract water like hyaluronic acid
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Improve tissue oxygenation and microcirculation
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Reduce inflammation and promote skin regeneration
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Common Treatment Areas
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Fine lines and wrinkles
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Under-eye dark circles and thinning
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Acne scarring
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Crepey or loose skin
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Stretch marks
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Post-laser or microneedling recovery
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Rosacea or sensitive skin
What to Expect
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Procedure time: ~20–40 minutes
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Protocol: 2–4 sessions spaced 2–4 weeks apart, with maintenance every 6–9 months
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Downtime: Minimal – mild swelling, redness, or small bumps for 1–2 days
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Results: Gradual improvement over 2–6 weeks
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Longevity: 6–9 months (depending on product and skin condition)
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Risks and Side Effects
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Bruising, swelling, or redness at injection site
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Temporary headache or flu-like symptoms
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Drooping eyelids or uneven results (rare and usually temporary)
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Resistance or less effect over time with frequent use
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What are Polynucleotides Best For?
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People with:
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Dehydrated or dull skin
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Fine lines (especially early signs of aging)
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Thin or crepey skin under eyes or neck
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Sensitive or inflamed skin (e.g., rosacea)
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Great for those who want natural skin quality improvement, not volume​
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Our fees
1 session £180
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Book a free consultation with our principal Dr Belichka to discuss if the use of botox or fillers will be suitable for you.
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